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52 Articles in 52 Weeks: Landmark EM Articles 2013

52To provide a resource for evidence-based Emergency Medical education, this list of must-read landmark articles was created to supplement the Emergency Medicine (EM) internship year of training. There are 52 articles so that one article can be read at leisure each week of the year. I searched national databases and polled faculty at the University of Washington to identify articles that faculty would expect any EM resident to be familiar with or that they felt were practice-changing in EM. Articles were selected for the final list based on the quality of study design, sample size, and relevance for EM residents.

System Autdors Title Journal Year Abstract
Airway/ Respiratory Reed, MJ et al Can an Airway Assessment Score Predict Difficulty at Intubation in the Emergency Department? Emergency Medicine Journal 2005 Pubmed
Airway/ Respiratory Wells, PS et al Excluding pulmonary embolism at the bedside without diagnostic imaging: Management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and D-dimer. Annals of Internal Medicine 2001 Pubmed
Airway/ Respiratory Kheterpal, S et al Incidence and Predictors of Difficult and Impossible Mask Ventilation. Anesthesiology 2006 Pubmed
Airway/ Respiratory The Acute Respiratory Distress Syndrome Network Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome. New England Journal of Medicine 2000 Pubmed
Airway/ Respiratory Burton, JH et al Does End-Tidal Carbon Dioxide Monitoring Detect Respiratory Events Prior to Current Sedation Monitoring Practices? Academic Emergency Medicine 2006 Pubmed
Airway/ Respiratory Brochard, L et al Noninvasive Ventilation for Acute Exacerbations of Chronic Obstructive Pulmonary Disease. New England Journal of Medicine 1995 Pubmed
Airway/ Respiratory Kline, JA et al Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. Journal of Thrombosis and Haemostasis 2008 Pubmed
Airway/ Respiratory Weingart, SD et al Preoxygenation and prevention of desaturation during emergency airway management. Annals of Emergency Medicine 2012 Pubmed
Cardiology Mehta, S et al Routine vs Selective Invasive Strategies in Patients with Acute Coronary Syndromes: A Collaborative Meta-Analysis of Randomized Trials. Journal of the American Medical Association 2005 Pubmed
Cardiology Sgarbossa, E et al Electrocardiographic Diagnosis of Evolving Acute Myocardial Infarction in the Presence of Left Bundle-Branch Block. New England Journal of Medicine 1996 Pubmed
Cardiology Weigner, M et al Risk for Clinical Thromboembolism Associated with Conversion to Sinus Rhythm in Patients with Atrial Fibrillation Lasting Less than 48 Hours. Annals of Internal Medicine 1997 Pubmed
Cardiology Than, M et al 2-Hour Accelerated Diagnostic Protocol to Assess Patients With Chest Pain Symptoms Using Contemporary Troponins as the Only Biomarker: The ADAPT Trial. Journal of the American College of Cardiology 2012 Pubmed
Cardiology Quinn, J et al Prospective validation of the San Francisco Syncope Rule to predict patients with serious outcomes. Annals of Emergency Medicine 2006 Pubmed
Cardiology Wenzel, V et al A Comparison of Vasopressin and Epinephrine for Out-of-Hospital Cardiopulmonary Resuscitation. New England Journal of Medicine 2004 Pubmed
Cardiology Hypothermia After Cardiac Arrest Study Group Mild Therapeutic Hypothermia to Improve the Neurologic Outcome after Cardiac Arrest. New England Journal of Medicine 2002 Pubmed
Cardiology Wyse, DG et al A comparison of rate control and rhythm control in patients with atrial fibrillation. New England Journal of Medicine 2002 Pubmed
Cardiology Andersen, HR et al A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction. New England Journal of Medicine 2003 Pubmed
Gastrointestinal Palamidessi, N et al Nasogastric aspiration and lavage in emergency department patients with hematochezia or melena without hematemesis. Academic Emergency Medicine 2010 Pubmed
Gastrointestinal Villanueva, C et al Transfusion strategies for acute upper gastrointestinal bleeding. New England Journal of Medicine 2013 Pubmed
Gastrointestinal Lau, J et al Omeprazole Before Endoscopy in Patients with Gastrointestinal Bleeding. New England Journal of Medicine 2007 Pubmed
Immunology Lin, R et al Improved Outcomes in Patients with Acute Allergic Syndromes Who are Treated with Combined H1 and H2 Antagonists. Annals of Emergency Medicine 2000 Pubmed
Infectious disease Marik, PE et al The risk of catheter-related bloodstream infection with femoral venous catheters as compared to subclavian and internal jugular venous catheters: A systematic review of the literature and meta-analysis. Critical Care Medicine 2012 Pubmed
Infectious disease Medeiros, I and Saconato, H. Antibiotic prophylaxis for mammalian bites. Cochrane Database of Systematic Reviews 2001 Pubmed
Infectious disease Wong, C et al The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections. Critical Care Medicine 2004 Pubmed
Musculoskeletal Stiell, IG et al Decision Rules for the Use of Radiography in Acute Ankle Injuries. Journal of the American Medical Association 1993 Pubmed
Neuroscience Anderson, CS et al Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial. Lancet 2008 Pubmed
Neuroscience Perry, JJ et al High risk clinical characteristics for subarachnoid haemorrhage in patients with acute headache: prospective cohort study. British Medical Journal 2010 Pubmed
Neuroscience Johnston, SC et al Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Lancet 2007 Pubmed
Neuroscience Morgenstern, L et al Worst Headache and Subarachinoid Hemorrhage: Prospective, Modern Computed Tomography and Spinal Fluid Analysis. Annals of Emergency Medicine 1998 Pubmed
Neuroscience The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. New England Journal of Medicine 1995 Pubmed
Neuroscience Hacke, W et al Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. New England Journal of Medicine 2008 Pubmed
Pediatrics Holmes, J et al Validation of a Prediction Rule for the Identification of Children With Intra-abdominal Injuries After Blunt Torso Trauma. Annals of Emergency Medicine 2009 Pubmed
Pediatrics Kuppermann, N et al Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study. Lancet 2009 Pubmed
Pediatrics Altamimi, S et al Single-dose oral dexamethasone in the emergency management of children with exacerbations of mild to moderate asthma. Pediatric Emergency Care 2006 Pubmed
Pediatrics Berg, AT et al A Prospective Study of Recurrent Febrile Seizures. New England Journal of Medicine 1992 Pubmed
Renal/ urology Coll, DM et al Relationship of spontaneous passage of ureteral calculi to stone size and location as revealed by unenhanced helical CT. American Journal of Roentgenology 2002 Pubmed
Renal/ urology Luchs, JS et al Utility of hematuria testing in patients with suspected renal colic: correlation with unenhanced helical CT results. Urology 2002 Pubmed
Resuscitation Dellinger, RP et al Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock. Critical Care Medicine 2013 Pubmed
Resuscitation Rivers, E et al Early goal-directed therapy in the treatment of severe sepsis and septic shock. New England Journal of Medicine 2001 Pubmed
Resuscitation Jones, AE et al Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. Journal of the American Medical Association 2010 Pubmed
Trauma Hoffman, JR et al Selective cervical spine radiography in blunt trauma: methodology of the National Emergency X-Radiography Utilization Study (NEXUS). Annals of Emergency Medicine 1998 Pubmed
Trauma Bickell, WH et al Immediate Versus Delayed Fluid Resuscitation for Hypotensive Patients with Penetrating Torso Injuries. New England Journal of Medicine 1994 Pubmed
Trauma Stiell, IG et al The Canadian C-Spine Rule for Radiography in Alert and Stable Trauma Patients. Journal of the American Medical Association 2001 Pubmed
Trauma Stiell, IG et al The Canadian CT Head Rule for patients with minor head injury. Lancet 2001 Pubmed
Trauma Chi, JH et al Prehospital Hypoxia Affects Outcome in Patients with Traumatic Brain Injury: A Prospective Multicenter Study. Journal of Trauma 2006 Pubmed
Trauma Haydel, MJ et al Indications for Computed Tomography in Patients with Minor Head Injury. New England Journal of Medicine 2000 Pubmed
Trauma CRASH-2 trial collaborators Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010 Pubmed
Trauma Branney, SW et al Critical Analysis of Two Decades of Experience with Postinjury Emergency Department Thoracotomy in a Regional Trauma Center. Journal of Trauma 1998 Pubmed
Trauma Tsutsumi, S et al Effects of the Second National Acute Spinal Cord Injury Study of High-Dose Methylprednisolone Therapy on Acute Cervical Spinal Cord Injury-Results in Spinal Injuries Center. Spine 2006 Pubmed
Trauma MacKenzie, EJ et al A national evaluation of the effect of trauma-center care on mortality. New England Journal of Medicine 2006 Pubmed
Ultrasound Branney, SW et al Quantitative Sensitivity of Ultrasound in Detecting Free Intraperitoneal Fluid. Journal of Trauma 1995 Pubmed
Ultrasound Nagdev, AD et al Emergency department bedside ultrasonographic measurement of the caval index for noninvasive determination of low central venous pressure. Annals of Emergency Medicine 2010 Pubmed

Emily Junck, MD

Emily Junck, MD

Helicopter EMS Fellow
Auckland City Hospital
Auckland, New Zealand
Emily Junck, MD

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