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Diagnose on Sight: Diffuse Desquamating Dermatitis


stevens-johnson syndromeCase: An 84 year old female presents with five days of a diffuse rash. She had a seizure and was started on phenytoin 2 weeks ago. Her mouth, labia, and medial canthi are involved. There are scattered areas of desquamation comprising less than a tenth of her total body surface area. She is tachycardic and febrile. Her complete blood count differential is normal. What is the diagnosis?

Poll Results

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Lee H, Lim Y, Thirumoorthy T, Pang S. The role of intravenous immunoglobulin in toxic epidermal necrolysis: a retrospective analysis of 64 patients managed in a specialized centre. Br J Dermatol. 2013;169(6):1304-1309. [PubMed]
The Annals of Emergency Medicine – Decoding the Drug Eruption – It is Hard to Breathe When Your Vocal Cords Don’t Work! EM:RAP. Published February 2015.
Jeff Riddell, MD

Jeff Riddell, MD

ALiEM Assistant Editor
Diagnose on Sight series;
Medical Education Research Fellow
University of Washington / Harborview Medical Center
Jeff Riddell, MD

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