Which component of the pictured plant is the cause of gastrointestinal symptoms when ingested?
- Histamine
- Lectins
- Oxalates
- Ribosomal inhibiting proteins
- Saponin glycosides
This post has been peer-reviewed on behalf of ACMT by Blake Froberg, Bryan Judge, and Louise Kao
References
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- Barker BE, Farnes P, LaMarche PH. Peripheral blood plasmacytosis following systemic exposure to Phytolacca americana (pokeweed). Pediatrics. 1966 Sep; 38(3):490-3. PMID 5920416
- Domashevskiy AV, & Goss DJ. Pokeweed antiviral protein, a ribosome inactivating protein: activity, inhibition and prospects. Toxins, 2015. 7(2), 274–298. PMID 25635465
- Burrows GE, Tyrl RJ. Phytolaccaceae. Toxic Plants of North America. 2013. Wiley-Blackwell. Pp 864 – 869.
- Di R, & Tumer NE. Pokeweed antiviral protein: its cytotoxicity mechanism and applications in plant disease resistance. Toxins, 2015. 7(3), 755–772. PMID 25756953
- Hassan, Y, Ogg, S, & Ge, H. Expression of novel fusion antiviral proteins ricin a chain-pokeweed antiviral proteins (RTA-PAPs) in Escherichia coli and their inhibition of protein synthesis and of hepatitis B virus in vitro. BMC Biotechnology. 2018. 18(1), 47. PMID 30081895
- Zhabokritsky A, Mansouri S, & Hudak KA. Pokeweed antiviral protein alters splicing of HIV-1 RNAs, resulting in reduced virus production. RNA. 2014. 20(8), 1238–1247. PMID 24951553
- Jaeckle KA, & Freemon, FR. Pokeweed poisoning. Southern Medical Journal, 1981. 74(5), 639–640. PMID 7244729
- Soloway, RAG. “Pokeberries: A Grape Look Alike.” National Capital Poison Center, 8 Oct. 2019, www.poison.org/articles/2012-aug/pokeberries-and-grapes-look-alike.