ACMT Toxicology Visual Pearls – In “Spore” Taste

A 15-year-old male presents symptomatic several hours after inhaling spores of this mushroom as a home remedy for epistaxis. What is the presentation and pathophysiology of the toxic syndrome associated with this mushroom?
For a video of this mushroom in action: https://youtu.be/G_DXTlvvsco
- Dyspnea and cough from hypersensitivity alveolitis
- Flushing, nausea and vomiting from acetaldehyde accumulation
- Nausea, vomiting and hepatoxicity from RNA synthetase inhibition
- Seizures from reduced GABA production in the central nervous system
A 30-year-old female presents with left second finger pain with overlying erythema, warmth, and swelling the day after her cat bit her finger. She cannot fully extend the finger, it is tender and she has pain when it is passively extended. Her hand appears as shown above (Figure 1. Case courtesy of Kristina Kyle, MD).








