Dump the Myths, Not the Milk: Medication and Imaging Considerations for Lactating Patients in the Emergency Department

lactation myths with medications and imaging
The challenges in lactation are often compounded by outdated beliefs held by clinicians.  Most of the medications we administer in the emergency department (ED) do not warrant any interruption in expression or feeding of breastmilk. Most imaging we perform in the ED is safe in the lactating patient and likewise does not need interruption. Let us convince you to trash the phrase, “Pump and Dump” in the ED.

Most medications commonly given in the ED are safe in lactation

Evidence suggests medication transfer through breast milk is frequently overestimated, with actual infant exposure typically minimal for most medications commonly prescribed in emergency settings [1]. The majority of medications administered in the ED are compatible with continued breastfeeding or pumping without interruption [2]. The practice of “pumping and dumping” is harmful to infants and lactating adults given the many benefits of lactation [3, 4]. It can cause irreparable disruptions in supply, increased parental burden and stress, and is not medically indicated except in very rare circumstances (chemotherapeutics for example) [3, 4]. When uncertainty exists regarding medication safety during lactation, clinicians should consult evidence-based resources such as LactMed or the LactRx app [iphone] to provide informed recommendations. A brief summary table is provided below for quick reference on some common medications.

Medication ClassSafe in LactationCautions in Lactation
Analgesia
  • Acetaminophen [5]
  • Ibuprofen [6]
  • Opioids in routine doses: Oxycodone [7], Morphine [8], Hydromorphone [9],  Fentanyl [10]
  • ⚠️ Caution in very high doses or prolonged infusions of opioids
  • Data on oxycodone shows no adverse effects attributed to oxycodone in maternal doses up to 60 mg/day (~90 MME/day) [11], which is well within the range of typical short-term ED prescribing for acute pain [12]
Sedative Hypnotics
  • Propofol [13]
  • Ketamine [14]
  • Midazolam [15]
  • Safe to feed when awake
  • ⚠️ Caution in infusions and higher doses of long-acting benzodiazepines
Paralytics
  • Succinylcholine [16]
  • Rocuronium [17]
  • Safe to feed when no longer paralyzed; likely safe to feed even on infusions
Opioid Use Disorder
  • Buprenorphine [18]
  • Methadone [19]
  • Recommended to continue feeding
Antibiotics
  • Penicillins [20]
  • Cephalosporins [20]
  • Macrolides [20]
  • Metronidazole [21]
  • Doxycycline (≤21 days) [22]
  • ⚠️ Trimethoprim-sulfamethoxazole (Avoid in premature, ill or jaundiced and those with G6PD) [23]
Anti-hypertensives
  • Labetalol [24]
  • Nifedipine [25]
  • Captopril, Enalapril, Benzapril (Lisinopril—less data) [26]
  • HCTZ [27]
  • Furosemide [28]
  • ⚠️ Diuretics may decrease milk supply if dehydrated
  • ❌ ARBs (Losartan) — No safety data and other alternatives are safe [26]
Antidepressants
  • Sertraline [29]
  • Paroxetine [30]
  • Fluoxetine [31]
  • Citalopram [32]
  • Do not stop an effective antidepressant because of lactation. Risk of depression relapse outweighs the small differences in milk transfer.
  • ⚠️ Bupropion (case reports of infant seizures without causal link) [33]
  • ❌ Doxepin (case reports of infant respiratory depression, hypotonia) [34]
Anticonvulsants
  • Carbamazepine [35]
  • Valproic acid [36]
  • Phenytoin [37]
  • Lamotrigine [38]
  • ⚠️ Levetiracetam (levels can be high, monitor for somnolence) [39]
  • ⚠️ Topiramate (case reports of infant somnolence) [40]
  • ❌ Phenobarbital (Avoid due to high infant exposure and sedation risk) [41]

Most Imaging Performed in the ED is Safe in Lactation

Radiation Exposure

Radiation exposure from diagnostic imaging we typically use in the ED (CT, x-ray) is minimal and there is no need to interrupt nursing/pumping [42].

IV contrast

Iodinated and gadolinium contrast agents are safe and do not require interruption of breastfeeding [43]. Read more in the American College of Radiology 2025 ACR Manual on Contrast Media (start at page 94).

In suspected pulmonary embolism (PE), CT pulmonary angiography (CTPA) is preferred over V/Q scan in lactating patients due to contrast safety (no breastfeeding interruption required), speed and availability, and high rates of indeterminate V/Q scans requiring subsequent CTPA [43, 44].

Exception: In the rare circumstance where contrast is contraindicated (such as anaphylaxis) and a radioactive tracer is indicated (V/Q scan with Tc-99m MAA), the radioactivity does warrant separation from both patient contact and milk for a period of time determined by the rate of decay of the specific agent [45]. Keep expressed milk stored appropriately until radioactivity has been able to decay then it’s safe to feed [46].

References (AMA Format)

  1. Nauwelaerts N, Macente J, Deferm N, Bonan RH, Huang MC, Van Neste M, et al. Generic workflow to predict medicine concentrations in human milk using physiologically-based pharmacokinetic (PBPK) modelling—a contribution from the ConcePTION project. Pharmaceutics. 2023;15(5):1469. doi:10.3390/pharmaceutics15051469
  2. Premer C, Caruso K. Safety profile of the most ordered medications for breastfeeding patients in the emergency department. Am J Emerg Med. 2024;80:1-7. doi:10.1016/j.ajem.2024.02.042
  3. Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013;132(3):e796-e809. doi:10.1542/peds.2013-1985
  4. Meek JY, Noble L; Section on Breastfeeding. Policy statement: breastfeeding and the use of human milk. Pediatrics. 2022;150(1):e2022057988. doi:10.1542/peds.2022-057988
  5. Acetaminophen. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  6. Ibuprofen. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  7. Oxycodone. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  8. Morphine. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  9. Hydromorphone. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  10. Fentanyl. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  11. FDA drug label. Food and Drug Administration; 2024-2025.
  12. Zhu W, Chernew ME, Sherry TB, Maestas N. Initial opioid prescriptions among US commercially insured patients, 2012-2017. N Engl J Med. 2019;380(11):1043-1052. doi:10.1056/NEJMsa1807069
  13. Propofol. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  14. Ketamine. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  15. Midazolam. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  16. Succinylcholine. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  17. Rocuronium. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  18. Buprenorphine. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  19. Methadone. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  20. Spencer JP, Thomas S, Trondsen Pawlowski RH. Medication safety in breastfeeding. Am Fam Physician. 2022;106(6):638-644.
  21. Metronidazole. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  22. Doxycycline. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  23. Trimethoprim-sulfamethoxazole. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  24. Labetalol. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  25. Nifedipine. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  26. Park K. Management of women with acquired cardiovascular disease from pre-conception through pregnancy and postpartum: JACC Focus Seminar 3/5. J Am Coll Cardiol. 2021.
  27. Hydrochlorothiazide. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  28. Furosemide. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  29. Sertraline. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  30. Paroxetine. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  31. Fluoxetine. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  32. Citalopram. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  33. Bupropion. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  34. Doxepin. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  35. Carbamazepine. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  36. Valproic acid. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  37. Phenytoin. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  38. Lamotrigine. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  39. Levetiracetam. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  40. Topiramate. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  41. Phenobarbital. In: Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development; 2006.
  42. Naseri M, Shahsavan M, Salahshour F, et al. Effective dose for radiological procedures in an emergency department: a cross-sectional study. Radiat Prot Dosimetry. 2020;189(1):63-68. doi:10.1093/rpd/ncaa013
  43. ACR Committee on Drugs and Contrast Media. ACR Manual on Contrast Media. American College of Radiology; 2025.
  44. Falster C, Hellfritzsch M, Gaist TA, et al. Comparison of international guideline recommendations for the diagnosis of pulmonary embolism. Lancet Haematol. 2023;10(11):e922-e935. doi:10.1016/S2352-3026(23)00181-3
  45. El-Sayed Y, Phillips Heine R, Wharton KR, eds. Guidelines for Diagnostic Imaging During Pregnancy and Lactation. American College of Obstetricians and Gynecologists; 2017.
  46. Leide-Svegborn S, Ahlgren L, Johansson L, Mattsson S. Excretion of radionuclides in human breast milk after nuclear medicine examinations: biokinetic and dosimetric data and recommendations on breastfeeding interruption. Eur J Nucl Med Mol Imaging. 2016;43(5):808-821. doi:10.1007/s00259-015-3286-0
By |2026-03-24T13:23:44-07:00Mar 26, 2026|Ob/Gyn, Radiology, Tox & Medications|

Procedural Use of a Mini C-arm in the Emergency Department

C-arms are mobile, C-shaped X-ray units that allow dynamic imaging for a wide range of procedures in outpatient clinics, procedure suites, operating rooms, and even emergency departments. Their uses include: fracture reduction and fixation, hardware placement, joint injections, and other image-guided interventional procedures. They are available in a variety of sizes including a mini C-arm that is specifically designed for imaging smaller body parts such as the hands and wrists.

Mini C-arms in emergency departments (ED) are not commonplace but when available they are often in trauma centers and most commonly utilized by orthopedic surgeons. Literature on the use of mini C-arms in the ED has mostly been for distal forearm fractures, where they have been shown to facilitate safe and effective fracture reductions and reduce the need for repeat formal radiographs during reductions [1-4]. Although mini C-arms are not typically used by emergency medicine (EM) physicians, familiarity with this imaging modality may be a valuable skill, especially for trainees rotating on the orthopedics service.

This article reviews mini C-arm anatomy, fluoroscopic principles, radiation safety and equipment, and illustrates its application in a case of a distal radius fracture.

Mini C-arm structure

The C-arm’s name comes from the C-shape that connects the X-ray source on one side to the image detector on the other, allowing rotation around the patient (Figure 1).

Anatomy of a mini c-arm machine illustration

Figure 1. Anatomy of a mini c-arm machine

How it works

  1. The operator controls acquisition of images through a foot pedal (allowing single images or live imaging).
  2. X-rays are generated through a tube which diverge out in a cone-like projection and pass through structures such as bone, which absorb X-rays differently based on characteristics like density and tissue thickness.
  3. After passing through structures, X-rays are absorbed on the opposite side by an image detector.
  4. The image detector converts this radiation to light, which is then processed by a computer to create a digital image visible on the monitor.

The C-arm has a rotation mechanism and an adjustable arm with various joints that allow movements in multiple planes. It allows orbital rotation, vertical and lateral movements, tilt, or swivel (Figure 2).

Maneuverability of a mini c-arm illustration

Figure 2: Maneuverability of a mini c-arm

How to set up a mini C-arm

  1. Plug in the device to a power source
  2. Turn on the switch to power on the device
  3. Use the monitor and/or keyboard to set up a study (some monitors are touch screen)
  4. Enter patient information
    • Find and select the option to begin study
    • Adjust the C-arm to the desired position
  5. Position the body part of interest flat and center on the detector
  6. Place the foot pedal in an easy to reach position
  7. Ensure that everyone in the room has radioprotective equipment (see radiation safety and equipment below)
  8. Step on the foot pedal to obtain an image or activate live imaging (review individual devices manuals to determine function of pedals)
  9. Save desired images

How to interpret images on a mini C-arm

Interpreting an image with a mini C-arm requires familiarity with fundamental radiographic principles related to image projection.

Laterality:

Unlike formal radiographs which include left or right markers, orientation of fluoroscopic images on a mini C-arm will be displayed based on the orientation of the image detector.

To illustrate this, in Figure 3, the right hand is rested with the palm resting directly on the image detector. On the monitor, the image appears as if the operator were directly looking at the hand, with the thumb on the left-most side. Most C-arms allow inversion of images on the monitor if another orientation is preferred.

Note: The X-ray beam travels from dorsal (posterior) to palmar (anterior), corresponding to a posteroanterior (PA) view.

Illustrated mini C-arm image of hand in posteroanterior view.

Figure 3: Illustrated mini C-arm image of hand in posteroanterior view

Magnification and depth

The relative distance between the X-ray source, the object, and the image detector affects image magnification and apparent depth of structures. To put it simply: the closer an object is to an X-ray source, the more magnified it appears; the closer an object is to the image detector, the less magnified it appears. This is analogous to the size of a shadow formed when a finger is moved closer to a light source. This principle affects image interpretation and highlights the importance of standardized positioning when obtaining images [5].

To illustrate this effect, we can consider the lateral view of the hand. Starting from the position in Figure 3, the hand can be supinated so that the ulnar aspect rests on the detector producing a lateral view (Figure 4). In this orientation, the thumb and second metacarpal may appear slightly magnified because they are now closer to the X-ray source. This also applies to the relative appearance of the radius and ulna.

Illustrated mini C-arm image of hand in lateral view

Figure 4: Illustrated mini C-arm image of hand in lateral view

As an analogy, imagine using a mini C-arm to image a rubber duck. If the duck is placed flat on the detector, the part closest to the X-ray source—the head—will appear slightly magnified. If the duck has an abnormally long neck that brings the head closer to the X-ray source, this magnification increases further (Figure 5). This same concept explains the apparent difference in heart size between posteroanterior (PA) and anteroposterior (AP) chest radiographs.

llustrated mini C-arm image of rubber duck

Figure 5: Illustrated mini C-arm image of rubber duck

This concept is important when using the mini C-arm for fracture reduction. You often want to capture as much of the entire body part as possible in the X-ray image while decreasing magnification, which means you will position the extremity directly against the image detector as far away as possible from the X-ray source while performing a reduction.

Radiation safety and protection

C-arms, like standard X-rays, emit ionizing radiation. Although most of the radiation is directed at patients, interactions between X-rays and surrounding matter produce scatter radiation, which is the primary source of radiation exposure to personnel. Repeated exposure is associated with increased lifetime risk of cancer, cataracts, thyroid issues including cancer, and fertility issues [6].

Radiation dose is measured in various units, including millirem (mrem) [5]. For context:

  • Average background radiation exposure (due to cosmic rays, radioactive elements in earth’s crust, etc) to U.S. residents is on average 310 mrem/year or <1 mrem/day
  • A cross country flight from NY to LA is ~5 mrem
  • A chest x-ray is ~10 mrem
  • A CT abdomen/pelvis is ~1,000 mrem

A benefit of the mini C-arm is that it emits less radiation than a standard-sized C-arm [8, 9]. In pediatric studies of distal forearm reductions performed with mini C-arm fluoroscopy, the estimated radiation exposure per case ranged from approximately 30 to 80 mrem, with lower exposures observed when trainees had completed radiation safety training, likely reflecting behavioral changes including fewer image acquisitions and shorter fluoroscopy activation [10]. Thus image acquisition should be intentional to reduce unnecessary radiation to both patients and personnel.

Radiation exposure follows the inverse square law, where if you double your distance from the X-ray source, you reduce exposure by one-fourth the original intensity. When possible, standing further away (at least 1 meter) from the X-ray source is recommended to reduce exposure (Figure 6) [5].

Additionally, use of radiation protective equipment such as lead aprons, thyroid shields, and leaded glasses, can significantly attenuate scatter radiation [8]. See Figure 7.

Inverse square law of radiation

Figure 6: Inverse square law of radiation

Radiation protective equipment

Figure 7: Radiation protective equipment

Bottom line:

  • Image only when necessary
  • Stand at least 1 meter away from the X-ray source when feasible
  • Utilize appropriate radiation protective equipment
  • By adhering to these principles, radiation exposure can be minimized when using a mini C-arm

Case: Distal radius fracture reduction with mini C-arm fluoroscopy

You are rotating through orthopedics and holding the consult pager. A 30-year-old patient presents to the ED after falling on their right outstretched hand, resulting in a deformity to the right distal forearm.

On examination, the skin appears intact and distal neurovascular exam is normal. Formal three-view wrist radiographs show an impacted, dorsally angulated transverse distal radius fracture without intra-articular extension.

Your senior recommends a reduction under fluoroscopy with your assistance. You perform a hematoma block, apply finger traps, and suspend the extremity vertically under ~10 lbs of traction. While the arm remains in traction, you bring the mini C-arm into the room and apply lead shields.

Obtaining images:

  1. Position the C-arm so that the image detector is near the affected arm. For a reduction, you should obtain PA and lateral views (oblique views are excluded in this example for simplicity).
  2. To obtain a PA view, ensure the palmar side of the distal forearm is against the detector (Figure 8).
  3. To obtain a lateral view, place the ulnar aspect of the distal forearm against the detector (Figure 9).

Note: Since the forearm is suspended in traction, sometimes you will need to rotate the mini C-arm around the extremity to obtain the correct alignment, instead of manipulating the arm.

Illustrated mini C-arm image of a distal radius fracture in posteroanterior view

Figure 8: Illustrated mini C-arm image of a distal radius fracture in posteroanterior view

\Illustrated mini C-arm image of a distal radius fracture in lateral view

Figure 9: Illustrated mini C-arm image of a distal radius fracture in lateral view

Important radiographic measurements:

In these views, assess radiographic parameters such as radial height, radial inclination, ulnar variance, and volar versus dorsal angulation angles (Supplemental Figures 1 and 2).

Post-reduction imaging:

Once the fracture appears appropriately reduced, obtain repeat C-arm images prior to applying a splint (Figure 10). After splint placement, obtain another set of images to confirm the reduction was maintained. Finally, order a formal post-reduction three-view wrist radiograph.

Illustrated mini C-arm images of a post-reduction distal radius fracture

Figure 10: Illustrated mini C-arm images of a post-reduction distal radius fracture

Restrictions on the use of fluoroscopy

Before using a mini C-arm, clinicians should confirm that they are appropriately credentialed and permitted to operate the device under local or state regulations, as fluoroscopy use laws differ across states and countries. Alternatively, a fluoroscopy credentialed radiation technologist can operate the device while the clinician performs the reduction.

Conclusions

Mini C-arms are a useful imaging modality available in select emergency departments. With an understanding of proper device operation and radiographic concepts such as image projection and radiation safety, the mini C-arm can be an effective tool to facilitate procedures such as distal radius fracture reduction. Although ultrasound remains the primary imaging modality for many procedures in the emergency department, the mini C-arm may potentially be a useful adjunct in other ED procedures such as joint aspirations and could warrant future exploration.

Measurements of the distal radius in posteroanterior view

Supplemental Figure 1: Measurements of the distal radius in posteroanterior view

Measurements of the distal radius in lateral view

Supplemental Figure 2: Measurements of the distal radius in lateral view

References

  1. Lee SM, Orlinsky M, Chan LS. Safety and effectiveness of portable fluoroscopy in the emergency department for the management of distal extremity fractures. Ann Emerg Med. 1994;24(4):725-730. doi:10.1016/S0196-0644(94)70284-5. PMID: 7998561
  2. Lee MC, Stone NE 3rd, Ritting AW, et al. Mini-C-arm fluoroscopy for emergency-department reduction of pediatric forearm fractures. J Bone Joint Surg Am. 2011;93(15):1442-1447. doi:10.2106/JBJS.J.01052. PMID 21915550 
  3. Dailey SK, Miller AR, Kakazu R, Wyrick JD, Stern PJ. The effectiveness of mini-C-arm fluoroscopy for the closed reduction of distal radius fractures in adults: a randomized controlled trial. J Hand Surg Am. 2018;43(10):927-931. doi:10.1016/j.jhsa.2018.02.015. PMID: 29573894
  4. Sumko MJ, Hennrikus WL, Slough J, King S. Measurement of radiation exposure when using the mini C-arm in pediatric orthopaedics. J Pediatr Orthop. 2016;36(2):122-125. doi:10.1097/BPO.0000000000000418. PMID: 25730377
  5. Bushberg JT, Seibert JA, Leidholdt EM Jr, Boone JM. The essential physics of medical imaging. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2012.
  6. Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for Ionizing Radiation. Atlanta, GA: US Department of Health and Human Services; 1999. Available from: https://www.ncbi.nlm.nih.gov/books/NBK597577/
  7. Centers for Disease Control and Prevention. Radiation Thermometer. Updated January 2, 2024. Accessed December 26, 2025. https://www.cdc.gov/radiation-emergencies/causes/radiation-thermometer.html
  8. Giordano BD, Ryder S, Baumhauer JF, DiGiovanni BF. Exposure to direct and scatter radiation with use of mini-C-arm fluoroscopy. J Bone Joint Surg Am. 2007;89(5):948-952. doi:10.2106/JBJS.F.00733. PMID: 17473130
  9. Giordano BD, Baumhauer JF, Morgan TL, Rechtine GR. Patient and surgeon radiation exposure: comparison of standard and mini-C-arm fluoroscopy. J Bone Joint Surg Am. 2009;91(2):297-304. doi:10.2106/JBJS.H.00407. PMID: 19181973
  10. Gendelberg D, Hennrikus W, Slough J, King S. A radiation safety training program results in reduced radiation exposure for orthopedic residents using the mini C-arm. J Pediatr Orthop. 2015;35(8):e123-e129. doi:10.1097/BPO.0000000000000345. PMID: 26566977
By |2025-12-30T18:08:43-08:00Dec 31, 2025|Orthopedic, Radiology|

SAEM Clinical Images Series: When it is Not Just a Knot

knot

A 12-year-old male with a history of hydrocephalus status post ventriculoperitoneal (VP) shunt placement presented with an abdominal “knot.” The patient’s mother noticed the knot two days ago, on the right anterolateral thorax, which has steadily been increasing in size. The patient had no known trauma to the area or had been bitten or stung by any insect. He has otherwise been complaining of a headache, generalized, without positional changes, improved with home acetaminophen, ice pack, and rest. There were otherwise no associated vision changes, nausea, vomiting, mental status changes, or fever.

Vitals: T-36.2°C; HR 74 bpm; BP 144/75 mm Hg; RR 20; O2 Sat 96% RA

General: Well-appearing teenager in NAD.

HEENT: NC/AT. PERRL approximately 2-3 mm bilaterally. EOMI.

Neck: Supple, no meningismus.

Chest Wall: Induration to the right anterolateral thorax 5 cm x 4 cm without erythema, fluctuance, or drainage, non-tender to palpation.

Neurological: Alert. No focal neurological deficit observed.

The cause of the knot is subcutaneous cerebrospinal fluid from a shunt malfunction. The ultrasound images show characteristic “cobblestoning,” indicating fluid in the subcutaneous tissue, around a linear hyperechoic object, the catheter of the VP shunt. On the plain film imaging, a disconnect was found between the thoracic and abdominal portions of the VP shunt. Up to 80% of patients with VP shunts will have experienced a shunt malfunction after 12 years, according to one study, with fractured tubing causing shunt failure in around 15% of all cases (1).

Nausea, vomiting, headache, irritability, or decreased mental status are common but nonspecific findings in shunt malfunction. Pediatric patients may present with other signs such as bulging fontanelles, increasing head circumference, or feeding and behavioral changes. An increase in the interval ventricular size can be seen in neuroimaging but can be absent in as many as 20% of patients (2). If there is a high degree of clinical suspicion for shunt malfunction, normal or unchanged neuroimaging should not preclude neurosurgical consultation.

Take-Home Points

  • In the United States, mechanical causes of VP shunt malfunction are the most common presentation, such as catheter obstruction, fracture along the clavicle or ribs, degradation of tubing, and migration of the distal catheter due to changes in height or weight.
  • Rarely, patients can develop an accumulation of CSF at the distal catheter of the VP shunt due to migration into the abdominal wall forming an abdominal pseudocyst.
  • In patients with VP shunts, abdominal complications should be considered as a sign of shunt malfunction.
  • Consider pertinent physical exam findings and POCUS to confirm the diagnosis of shunt malfunction at the distal catheter.

  • Sainte-Rose C, Piatt JH, Renier D, Pierre-Kahn A, Hirsch JF, Hoffman HJ, Humphreys RP, Hendrick EB. Mechanical complications in shunts. Pediatr Neurosurg. 1991-1992;17(1):2-9. doi: 10.1159/000120557. PMID: 1811706.

  • Reynolds RA, Ahluwalia R, Krishnan V, Kelly KA, Lee J, Waldrop RP, Guidry B, Hengartner AC, McCroskey J, Arynchyna A, Staulcup S, Chen H, Hankinson TC, Rocque BG, Shannon CN, Naftel R. Risk factors for unchanged ventricles during pediatric shunt malfunction. J Neurosurg Pediatr. 2021 Sep 24;28(6):703-709. doi: 10.3171/2021.6.PEDS2125. PMID: 34560626.

SAEM Clinical Images Series: Rectal Bulge

rectal bulge

A 13-month-old, full-term male presented due to intermittent emesis over a 3-week period. He and his parents had COVID one week prior to presentation. He had multiple episodes of non-bloody, non-bilious vomit the day before and the day of presentation. Parents noted he had been listless and unable to tolerate food. The mother was also concerned that he was straining to have bowel movements and that a mass was coming out of his bottom on the ride to the hospital. Parents reported decreased activity, decreased appetite, and decreased urine output. He was born via cesarean section due to breech presentation but had an otherwise uncomplicated prenatal history.

Constitutional: Fatigued.

Gastrointestinal: Diffuse abdominal tenderness. Reducible rectal bulge.

Skin: Pale.

Anion Gap: 19

COVID-19: Positive

WBC: 11.9

Limited Abdominal Ultrasound: A large intussusception is noted, which appears to extend at least to the descending/sigmoid colon.

XR Abdomen: Few prominent, featureless bowel loops with air-fluid levels. No gastric distention.

Air or hydrostatic enemas have a 70-85% success rate in current literature. These are often done under either fluoroscopic or ultrasound guidance. A delayed repeat enema can be done in cases where the initial enema resolved some of the intussusception. If the initial measures are unsuccessful, the patient is unstable, or the patient is exhibiting signs of peritonitis or bowel perforation, surgical management is the next step. This can either be done laparoscopically or open. In this patient’s case, an air enema was attempted but he ultimately required surgery. The surgery was laparoscopic, and he was discharged the same day.

Take-Home Points

  • Consider intussusception in any child with a URI (including COVID-19) and a rectal bulge.
  • Although this patient had a formal ultrasound, POCUS can be a useful tool in the ED to identify and expedite intussusception treatment. The classic “bullseye sign” was seen on this patient’s ultrasound.

  • Mandeville K, Chien M, Willyerd FA, Mandell G, Hostetler MA, Bulloch B. Intussusception: clinical presentations and imaging characteristics. Pediatr Emerg Care. 2012 Sep;28(9):842-4. doi: 10.1097/PEC.0b013e318267a75e. PMID: 22929138.
  • Siafakas C, Vottler TP, Andersen JM. Rectal prolapse in pediatrics. Clin Pediatr (Phila). 1999 Feb;38(2):63-72. doi: 10.1177/000992289903800201. PMID: 10047938.

SAEM Clinical Images Series: Clot in Transit

clot

A 67-year-old male with a past medical history of CHF, MI, hypertension, and diabetes presented to the ED with complaints of headache, chest pain, and dyspnea for the past four days. He stated that he has been without his medications for the past few months due to cost. He denied any past surgical history. He stated that he primarily presented because he felt like “my blood pressure is high”.

Cardiovascular: Tachycardic, 2+ pedal edema bilaterally

Respiratory: Tachypneic, decreased breath sounds bilaterally, ronchi/wheezes bilaterally

Skin: Diaphoretic

Troponin I: 0.13 (elevated)

BNP: 1,504

The findings in this picture are of a phenomenon called clot in transit. Via point-of-care ultrasound we were able to visualize part of a thrombus as it journeyed from the right side of the heart to the lungs, becoming a pulmonary embolism. In studies regarding the subject, clot in transit has been found in 3-18% of patients with acute PE. Unfortunately, clot in transit is associated with higher mortality in patients with acute PE. While not fully understood, part of the reason for this may be related to the fact that the patient population that this finding is found in tends to be sicker with higher rates of CHF, cancer, and immobilization. Additionally, increased mortality may be related to PE size given that the clot must be large enough to be seen by ultrasound. Studies have recorded clot in the 30-day mortality rates for patients with acute PE and visualized clot in transit to be 9-45%.

Take-Home Points

  • Point of care US is an essential tool for quickly assessing and appropriately treating patients. This patient’s story was very consistent with a CHF exacerbation but POCUS allowed us to quickly identify a PE and get the patient on track to definitive management.
  • Clot in transit once identified requires immediate action because it is associated with such high mortality in patients.
  • There remains more research to be done on the matter but it appears that clot in transit signifies a need for advanced forms of PE management (thrombolysis or thrombectomy ) to improve mortality in comparison to normal systemic anticoagulation.

  • Athappan G, Sengodan P, Chacko P, Gandhi S. Comparative efficacy of different modalities for treatment of right heart thrombi in transit: a pooled analysis. Vasc Med. 2015 Apr;20(2):131-8. doi: 10.1177/1358863X15569009. PMID: 25832601.
  • Barrios D, Rosa-Salazar V, Jiménez D, Morillo R, Muriel A, Del Toro J, López-Jiménez L, Farge-Bancel D, Yusen R, Monreal M; RIETE investigators. Right heart thrombi in pulmonary embolism. Eur Respir J. 2016 Nov;48(5):1377-1385. doi: 10.1183/13993003.01044-2016. Epub 2016 Oct 6. PMID: 27799388.
  • FREY J, BROWNBACK K. Clot in transit: A dilema of medical or surgical management. Chest. 2021;160(4):A2190. doi: 10.1016/j.chest.2021.07.1932.
  • Garvey S, Dudzinski DM, Giordano N, Torrey J, Zheng H, Kabrhel C. Pulmonary embolism with clot in transit: An analysis of risk factors and outcomes. Thromb Res. 2020;187:139-147. doi: 10.1016/ j.thromres.2020.01.006.

SAEM Clinical Images Series: When Needles Go Beyond Sewing and Acupuncture

needles

A 64-year-old male with a history of bipolar 1 disorder, PTSD, anxiety, depression, obsessive-compulsive disorder, GERD, and HTN presented to the ED with the chief complaint of foreign body and self-injury. He reported years of sticking sewing needles into his right arm, most recently yesterday. He explained that inserting needles makes him feel better with mild associated pain. He endorsed suicidal ideas, elaborating that he did not want to stop injuring himself. He also reported depression and wished that he was not alive. He stated that he had told his therapist that he didn’t want to present to the ED today and added that he wanted to leave the ED and did not want to be seen by the psych team. He denied homicidal ideation.

Extremities: When palpating the right forearm, multiple linear hard objects are felt in the subcutaneous tissue. The patient can flex/extend the wrist, supinate and pronate, and flex/extend the elbow without issue. No erythema or fluctuance. No obvious insertion site noted.

Numerous linear metallic foreign bodies are present throughout the right forearm; several new foreign bodies are noted. Bony exam is significantly limited due to the presence of numerous (greater than 50) linear metallic densities throughout the forearm. Mild to moderate degenerative changes of the wrist and elbow are noted.

Take-Home Points

  • Removal of metallic foreign bodies is an individualized risk vs benefit decision based on the following: signs of infection, suspected level of contamination, type of metal, cooperativeness of the patient, location nearby vital structures, cosmetic deformity, and pain. When the risk of removal outweighs the benefits or if the patient does not desire removal, foreign body removal is not always needed.
  • Regarding prophylaxis, antibiotics need not be routinely administered if the wound is clean. Tetanus vaccination status should be reviewed, and the vaccine (Tdap) and/or potentially tetanus immune globulin should be administered if indicated.

  • Rupert J, Honeycutt JD, Odom MR. Foreign Bodies in the Skin: Evaluation and Management. Am Fam Physician. 2020 Jun 15;101(12):740-747. PMID: 32538598.
  • Lane JC, Mabvuure NT, Hindocha S, Khan W. Current concepts of prophylactic antibiotics in trauma: a review. Open Orthop J. 2012;6:511-7. doi: 10.2174/1874325001206010511. Epub 2012 Nov 30. PMID: 23248721; PMCID: PMC3522105.

By |2024-10-15T10:59:39-07:00Oct 25, 2024|Psychiatry, Radiology, SAEM Clinical Images|

Trick of the Trade: Cut IV extension tubing for 2-person ultrasound guided nerve block

illustration nerve block ultrasound guided needle

Ultrasound-guided procedures are difficult enough just identifying the anatomy. Performing a nerve block with the ultrasound in one hand and the needle in the other hand adds extra challenges. The simplest 1-person approach involves attaching a syringe with local anesthetic directly to the end of the procedural needle. A 2-person approach involves attach the syringe to a custom tubing-needle setup such as below. However, this custom setup may not be readily available.

IV and extension tubing attached to needle

Trick of Trade: Cut Standard IV Extension Tubing

Required equipment:

  • Ultrasound linear probe
  • 10 cc syringe
  • IV tubing
  • Procedural needle
  • Shears

IV extension injection port

Almost all standard IV extension tubing that connects IV fluid bags to a peripheral IV have an injection port near the downstream end.

  1. Clamp the IV tubing just upstream from the injection port and cut off all the unused upstream IV tubing.
  2. Attach a 10 cc syringe with local anesthetic to the injection port.
  3. Attach the other end of this IV tubing (Luer lock attachment) to the procedural needle.
  4. Prime the IV line with the anesthetic.
  5. Perform the nerve block with one person advancing the needle under ultrasound guidance, while the other person aspirates and injects the anesthetic when needed.

Video: 2-person ultrasound-guided nerve block with cut IV tubing

Bonus Tip: This approach is applicable to many procedures requiring aspiration or instillation of anesthetic, such as peritonsillar abscess aspiration.

Read more from the Tricks of the Trade series.

By |2024-10-23T07:23:46-07:00Oct 23, 2024|Neurology, Tricks of the Trade, Ultrasound|
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