52 Articles in 52 Weeks: Landmark EM Articles 2013

To provide a resource for evidence-based Emergency Medical education, this list of must-read landmark articles was created to supplement the Emergency Medicine (EM) internship year of training. There are 52 articles so that one article can be read at leisure each week of the year. I searched national databases and polled faculty at the University of Washington to identify articles that faculty would expect any EM resident to be familiar with or that they felt were practice-changing in EM. Articles were selected for the final list based on the quality of study design, sample size, and relevance for EM residents.

System	Autdors	Title	Journal	Year	Abstract
Airway/ Respiratory	Reed, MJ et al	Can an Airway Assessment Score Predict Difficulty at Intubation in the Emergency Department?	Emergency Medicine Journal	2005	Pubmed
Airway/ Respiratory	Wells, PS et al	Excluding pulmonary embolism at the bedside without diagnostic imaging: Management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and D-dimer.	Annals of Internal Medicine	2001	Pubmed
Airway/ Respiratory	Kheterpal, S et al	Incidence and Predictors of Difficult and Impossible Mask Ventilation.	Anesthesiology	2006	Pubmed
Airway/ Respiratory	The Acute Respiratory Distress Syndrome Network	Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome.	New England Journal of Medicine	2000	Pubmed
Airway/ Respiratory	Burton, JH et al	Does End-Tidal Carbon Dioxide Monitoring Detect Respiratory Events Prior to Current Sedation Monitoring Practices?	Academic Emergency Medicine	2006	Pubmed
Airway/ Respiratory	Brochard, L et al	Noninvasive Ventilation for Acute Exacerbations of Chronic Obstructive Pulmonary Disease.	New England Journal of Medicine	1995	Pubmed
Airway/ Respiratory	Kline, JA et al	Prospective multicenter evaluation of the pulmonary embolism rule-out criteria.	Journal of Thrombosis and Haemostasis	2008	Pubmed
Airway/ Respiratory	Weingart, SD et al	Preoxygenation and prevention of desaturation during emergency airway management.	Annals of Emergency Medicine	2012	Pubmed
Cardiology	Mehta, S et al	Routine vs Selective Invasive Strategies in Patients with Acute Coronary Syndromes: A Collaborative Meta-Analysis of Randomized Trials.	Journal of the American Medical Association	2005	Pubmed
Cardiology	Sgarbossa, E et al	Electrocardiographic Diagnosis of Evolving Acute Myocardial Infarction in the Presence of Left Bundle-Branch Block.	New England Journal of Medicine	1996	Pubmed
Cardiology	Weigner, M et al	Risk for Clinical Thromboembolism Associated with Conversion to Sinus Rhythm in Patients with Atrial Fibrillation Lasting Less than 48 Hours.	Annals of Internal Medicine	1997	Pubmed
Cardiology	Than, M et al	2-Hour Accelerated Diagnostic Protocol to Assess Patients With Chest Pain Symptoms Using Contemporary Troponins as the Only Biomarker: The ADAPT Trial.	Journal of the American College of Cardiology	2012	Pubmed
Cardiology	Quinn, J et al	Prospective validation of the San Francisco Syncope Rule to predict patients with serious outcomes.	Annals of Emergency Medicine	2006	Pubmed
Cardiology	Wenzel, V et al	A Comparison of Vasopressin and Epinephrine for Out-of-Hospital Cardiopulmonary Resuscitation.	New England Journal of Medicine	2004	Pubmed
Cardiology	Hypothermia After Cardiac Arrest Study Group	Mild Therapeutic Hypothermia to Improve the Neurologic Outcome after Cardiac Arrest.	New England Journal of Medicine	2002	Pubmed
Cardiology	Wyse, DG et al	A comparison of rate control and rhythm control in patients with atrial fibrillation.	New England Journal of Medicine	2002	Pubmed
Cardiology	Andersen, HR et al	A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction.	New England Journal of Medicine	2003	Pubmed
Gastrointestinal	Palamidessi, N et al	Nasogastric aspiration and lavage in emergency department patients with hematochezia or melena without hematemesis.	Academic Emergency Medicine	2010	Pubmed
Gastrointestinal	Villanueva, C et al	Transfusion strategies for acute upper gastrointestinal bleeding.	New England Journal of Medicine	2013	Pubmed
Gastrointestinal	Lau, J et al	Omeprazole Before Endoscopy in Patients with Gastrointestinal Bleeding.	New England Journal of Medicine	2007	Pubmed
Immunology	Lin, R et al	Improved Outcomes in Patients with Acute Allergic Syndromes Who are Treated with Combined H1 and H2 Antagonists.	Annals of Emergency Medicine	2000	Pubmed
Infectious disease	Marik, PE et al	The risk of catheter-related bloodstream infection with femoral venous catheters as compared to subclavian and internal jugular venous catheters: A systematic review of the literature and meta-analysis.	Critical Care Medicine	2012	Pubmed
Infectious disease	Medeiros, I and Saconato, H.	Antibiotic prophylaxis for mammalian bites.	Cochrane Database of Systematic Reviews	2001	Pubmed
Infectious disease	Wong, C et al	The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections.	Critical Care Medicine	2004	Pubmed
Musculoskeletal	Stiell, IG et al	Decision Rules for the Use of Radiography in Acute Ankle Injuries.	Journal of the American Medical Association	1993	Pubmed
Neuroscience	Anderson, CS et al	Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial.	Lancet	2008	Pubmed
Neuroscience	Perry, JJ et al	High risk clinical characteristics for subarachnoid haemorrhage in patients with acute headache: prospective cohort study.	British Medical Journal	2010	Pubmed
Neuroscience	Johnston, SC et al	Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack.	Lancet	2007	Pubmed
Neuroscience	Morgenstern, L et al	Worst Headache and Subarachinoid Hemorrhage: Prospective, Modern Computed Tomography and Spinal Fluid Analysis.	Annals of Emergency Medicine	1998	Pubmed
Neuroscience	The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group.	Tissue plasminogen activator for acute ischemic stroke.	New England Journal of Medicine	1995	Pubmed
Neuroscience	Hacke, W et al	Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke.	New England Journal of Medicine	2008	Pubmed
Pediatrics	Holmes, J et al	Validation of a Prediction Rule for the Identification of Children With Intra-abdominal Injuries After Blunt Torso Trauma.	Annals of Emergency Medicine	2009	Pubmed
Pediatrics	Kuppermann, N et al	Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study.	Lancet	2009	Pubmed
Pediatrics	Altamimi, S et al	Single-dose oral dexamethasone in the emergency management of children with exacerbations of mild to moderate asthma.	Pediatric Emergency Care	2006	Pubmed
Pediatrics	Berg, AT et al	A Prospective Study of Recurrent Febrile Seizures.	New England Journal of Medicine	1992	Pubmed
Renal/ urology	Coll, DM et al	Relationship of spontaneous passage of ureteral calculi to stone size and location as revealed by unenhanced helical CT.	American Journal of Roentgenology	2002	Pubmed
Renal/ urology	Luchs, JS et al	Utility of hematuria testing in patients with suspected renal colic: correlation with unenhanced helical CT results.	Urology	2002	Pubmed
Resuscitation	Dellinger, RP et al	Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock.	Critical Care Medicine	2013	Pubmed
Resuscitation	Rivers, E et al	Early goal-directed therapy in the treatment of severe sepsis and septic shock.	New England Journal of Medicine	2001	Pubmed
Resuscitation	Jones, AE et al	Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.	Journal of the American Medical Association	2010	Pubmed
Trauma	Hoffman, JR et al	Selective cervical spine radiography in blunt trauma: methodology of the National Emergency X-Radiography Utilization Study (NEXUS).	Annals of Emergency Medicine	1998	Pubmed
Trauma	Bickell, WH et al	Immediate Versus Delayed Fluid Resuscitation for Hypotensive Patients with Penetrating Torso Injuries.	New England Journal of Medicine	1994	Pubmed
Trauma	Stiell, IG et al	The Canadian C-Spine Rule for Radiography in Alert and Stable Trauma Patients.	Journal of the American Medical Association	2001	Pubmed
Trauma	Stiell, IG et al	The Canadian CT Head Rule for patients with minor head injury.	Lancet	2001	Pubmed
Trauma	Chi, JH et al	Prehospital Hypoxia Affects Outcome in Patients with Traumatic Brain Injury: A Prospective Multicenter Study.	Journal of Trauma	2006	Pubmed
Trauma	Haydel, MJ et al	Indications for Computed Tomography in Patients with Minor Head Injury.	New England Journal of Medicine	2000	Pubmed
Trauma	CRASH-2 trial collaborators	Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.	Lancet	2010	Pubmed
Trauma	Branney, SW et al	Critical Analysis of Two Decades of Experience with Postinjury Emergency Department Thoracotomy in a Regional Trauma Center.	Journal of Trauma	1998	Pubmed
Trauma	Tsutsumi, S et al	Effects of the Second National Acute Spinal Cord Injury Study of High-Dose Methylprednisolone Therapy on Acute Cervical Spinal Cord Injury-Results in Spinal Injuries Center.	Spine	2006	Pubmed
Trauma	MacKenzie, EJ et al	A national evaluation of the effect of trauma-center care on mortality.	New England Journal of Medicine	2006	Pubmed
Ultrasound	Branney, SW et al	Quantitative Sensitivity of Ultrasound in Detecting Free Intraperitoneal Fluid.	Journal of Trauma	1995	Pubmed
Ultrasound	Nagdev, AD et al	Emergency department bedside ultrasonographic measurement of the caval index for noninvasive determination of low central venous pressure.	Annals of Emergency Medicine	2010	Pubmed