Upper Gastrointestinal Bleeding: Evidence-Based Treatment
Upper gastrointestinal bleeding remains a common reason for emergency department visits and is a major cause of morbidity, mortality, and medical care costs. Often when these patients arrive, the classic IV-O2-Monitor is initiated and hemodynamic stability is assessed. Some of the next steps often performed include:
- Determination of the site and rate of bleeding (upper vs lower)
- Initiation of proton pump inhibitors (PPIs)
- Somatostatin analogs if variceal bleeding is suspected
- Prophylactic antibiotics
- Packed red blood cell (PRBC) transfusion for low hemoglobin and hematocrit levels
What is the evidence for these treatments, and do they affect morbidity and mortality?



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It seems like a simple enough question: How do you diagnose and treat uncomplicated UTIs in older adults? The answer is: It depends. Part 1 of this post will discuss diagnosis of UTIs in this population, and part 2 will address treatment.