Cyclobenzaprine vs TCA Toxicity

CyclobenzaprineShould we treat a cyclobenzaprine (Flexeril) overdose similar to a tricyclic antidepressant (TCA) overdose? With the only difference between the commonly prescribed muscle relaxant, cyclobenzaprine, and the TCA amitriptyline consisting of a single double bond, should the emergency provider be concerned for life threatening arrhythmias in cyclobenzaprine overdose?

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By |2016-11-20T07:20:37-08:00Feb 13, 2014|Tox & Medications|

When the PERC Rule Fails

PEKline et al developed a clinical decision tool based on parameters that could be obtained from a brief initial assessment to reasonably exclude the diagnosis of pulmonary embolism (PE) without the use of D-dimer in order to prevent unnecessary cost and the use of medical resources. 1 Many of us have used the Pulmonary Embolism Rule-out Criteria (PERC) rule by now, but we should be clear on what it includes. Are we using it appropriately?

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AMA: 2 high risk myths and misconceptions

ExitSignPatients who leave the emergency department against medical advice (AMA) are at an increased risk of having a bad medical outcome, and can be a source of significant medicolegal risk to providers. Earlier we reviewed eight elements to address when signing a patient out AMA. There are two common myths regarding patients who leave AMA that can complicate an already difficult situation.

 

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By |2016-11-11T19:18:19-08:00Feb 10, 2014|Medicolegal|

BISAP, EHMRG, ORT: 3 New Medical Scores You’ve Never Heard Of

MDCalcLet’s face it. You’ve heard about the A-a gradient. And free water deficit. And even the APACHE-II score. But how useful are these in your daily practice? You don’t care that much if a patient has shunt physiology in the first case, nor exactly how much free water they’re lacking in the second. And in the third case, your clinical acumen is probably pretty good at predicting a sick patient’s mortality already. But what about the new medical scores of BISAP, EHMRG, and ORT?

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Blood Pressure Management in Adults (JNC 8 and ACEP Policy)

Black tonometer and heart isolated on whiteHypertension is one of the most common conditions seen in primary care clinics and emergency departments (EDs).  Frequently, patients are found to have asymptomatic hypertension and referred to EDs for management, despite the fact that rapidly lowering blood pressure is not necessary and may be harmful.  Yet many clinics still refer these patients for emergent management. In December 2013, the Eighth Joint National Committee (JNC 8) published a new, open-access, evidence-based hypertension guideline in JAMA.  They only cited randomized clinical control trials to answer three questions:

  1. Does initiating antihypertensive pharmacologic therapy at specific BP thresholds improve health outcomes?
  2. Does treatment with antihypertensive pharmacologic therapy to a specified BP goal lead to improvements in health outcomes?
  3. Do various antihypertensive drugs or drug classes differ in comparative benefits and harms on specific health outcomes? (more…)
By |2019-09-10T13:34:41-07:00Feb 5, 2014|Cardiovascular|
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