Ketofol: Is this the “Game Changer” of Procedural Sedation and Analgesia?

When talking about procedural sedation and analgesia, our goal is to minimize pain and anxiety, with the appropriate agent that matches the needs of our patient and the clinical scenario. So what are some qualities of this “ideal agent?”
In a perfect world, it would have:
- Minimal adverse effects
- Rapid onset and offset of action
- Pharmocokinetic predictability across a spectrum of patients



There was recently a great study published in the American Journal of Cardiology (2012) by Sharifi et al